Acetylation of H3K27 activated lncRNA NEAT1 and promoted hepatic lipid accumulation in non-alcoholic fatty liver disease via regulating miR-212-5p/GRIA3.

Hu, Min-Jie; Long, Mei; Dai, Rong-Juan

Hu, Min-Jie; Long, Mei; Dai, Rong-Juan.

Affiliation

Hu MJ; Department of Cardiothoracic Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, 421000, Hunan Province, People's Republic of China.
Long M; Department of Rheumatology, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, 421000, Hunan Province, People's Republic of China.
Dai RJ; Department of Infectious Diseases, The First Affiliated Hospital, Hengyang Medical School, University of South China, No.69, Chuanshan Road, Shigu District, Hengyang, 421000, Hunan Province, People's Republic of China. 1784868305@qq.com.

Mol Cell Biochem ; 477(1): 191-203, 2022 Jan.

Article in En | MEDLINE | ID: mdl-34652536

Subject(s)

Histones/genetics; Lipid Metabolism/physiology; Non-alcoholic Fatty Liver Disease/metabolism; RNA, Long Noncoding/metabolism; Receptors, AMPA/genetics; Acetylation; Case-Control Studies; Fatty Acids/pharmacology; Gene Expression Regulation/drug effects; Hep G2 Cells; Histones/metabolism; Humans; Lipid Metabolism/drug effects; Liver/drug effects; Liver/metabolism; Lysine/metabolism; MicroRNAs/genetics; Non-alcoholic Fatty Liver Disease/genetics; Receptors, AMPA/metabolism

Key words

Acetylation; GRIA3; H3K27; NAFLD; lncRNA NEAT1; miR-212-5p

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histones / Receptors, AMPA / Lipid Metabolism / RNA, Long Noncoding / Non-alcoholic Fatty Liver Disease Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: Mol Cell Biochem Year: 2022 Type: Article

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