The Inhibitory Receptor GPR56 (<i>Adgrg1</i>) Is Specifically Expressed by Tissue-Resident Memory T Cells in Mice But Dispensable for Their Differentiation and Function In Vivo.

Hsiao, Cheng-Chih; Kragten, Natasja A M; Piao, Xianhua; Hamann, Jörg; van Gisbergen, Klaas P J M

The Inhibitory Receptor GPR56 (Adgrg1) Is Specifically Expressed by Tissue-Resident Memory T Cells in Mice But Dispensable for Their Differentiation and Function In Vivo.

Hsiao, Cheng-Chih; Kragten, Natasja A M; Piao, Xianhua; Hamann, Jörg; van Gisbergen, Klaas P J M.

Affiliation

Hsiao CC; Department of Experimental Immunology, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Kragten NAM; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Centers, University of Amsterdam, 1066 CX Amsterdam, The Netherlands.
Piao X; Department of Pediatrics, Newborn Brain Research Institute, Weill Institute for Neuroscience, University of California, San Francisco, CA 94158, USA.
Hamann J; Department of Experimental Immunology, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
van Gisbergen KPJM; Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Centers, University of Amsterdam, 1066 CX Amsterdam, The Netherlands.

Cells ; 10(10)2021 10 06.

Article in En | MEDLINE | ID: mdl-34685654

Subject(s)

Cell Differentiation/immunology; Immunologic Memory; Receptors, G-Protein-Coupled/metabolism; T-Lymphocytes/immunology; Animals; CD8-Positive T-Lymphocytes/immunology; Cytokines/biosynthesis; Cytotoxicity, Immunologic; Gene Expression Regulation; Listeria/physiology; Lymphocytic choriomeningitis virus/physiology; Mice; Receptors, G-Protein-Coupled/genetics; Up-Regulation

Key words

GPR56; adhesion GPCR; inhibitory receptor; tissue-resident memory T cells

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Cell Differentiation / Receptors, G-Protein-Coupled / Immunologic Memory Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cells Year: 2021 Type: Article Affiliation country: Netherlands

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