Comparative study on the effect of aspirin, TP receptor antagonist and TxA<sub>2</sub> synthase inhibitor on the vascular tone of human saphenous vein and internal mammary artery.

Ozen, Gulsev; Aljesri, Khadija; Abdelazeem, Heba; Norel, Xavier; Turkyilmaz, Gulsum; Turkyilmaz, Saygin; Topal, Gokce

Comparative study on the effect of aspirin, TP receptor antagonist and TxA₂ synthase inhibitor on the vascular tone of human saphenous vein and internal mammary artery.

Ozen, Gulsev; Aljesri, Khadija; Abdelazeem, Heba; Norel, Xavier; Turkyilmaz, Gulsum; Turkyilmaz, Saygin; Topal, Gokce.

Affiliation

Ozen G; Department of Pharmacology, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey. Electronic address: gulsevozen@istanbul.edu.tr.
Aljesri K; Department of Pharmacology, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey.
Abdelazeem H; Université de Paris, INSERM, UMR-S 1148, CHU X. Bichat, 75018 Paris, France; Université Sorbonne Paris Nord, 93430 Villetaneuse, France; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Egypt.
Norel X; Université de Paris, INSERM, UMR-S 1148, CHU X. Bichat, 75018 Paris, France; Université Sorbonne Paris Nord, 93430 Villetaneuse, France.
Turkyilmaz G; Department of Cardiovascular Surgery, Bakirkoy Dr Sadi Konuk Education and Research Hospital Bakirkoy, Istanbul, Turkey.
Turkyilmaz S; Department of Cardiovascular Surgery, Bakirkoy Dr Sadi Konuk Education and Research Hospital Bakirkoy, Istanbul, Turkey.
Topal G; Department of Pharmacology, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey.

Life Sci ; 286: 120073, 2021 Dec 01.

Article in En | MEDLINE | ID: mdl-34688694

Subject(s)

Mammary Arteries/drug effects; Saphenous Vein/drug effects; Arachidonic Acid/metabolism; Aspirin/pharmacology; Benzofurans/pharmacology; Carbazoles/pharmacology; Enzyme Inhibitors/pharmacology; Female; Humans; Male; Mammary Arteries/metabolism; Muscle, Smooth, Vascular/metabolism; Phenylephrine/pharmacology; Receptors, Prostaglandin/metabolism; Receptors, Thromboxane/antagonists & inhibitors; Receptors, Thromboxane/drug effects; Receptors, Thromboxane/metabolism; Saphenous Vein/metabolism; Sulfonamides/pharmacology; Thromboxane A2/pharmacology; Thromboxane-A Synthase/antagonists & inhibitors; Thromboxane-A Synthase/drug effects; Thromboxane-A Synthase/metabolism; Thromboxanes/antagonists & inhibitors; Thromboxanes/metabolism; Vasoconstriction/drug effects

Key words

Aspirin; Internal mammary artery; Saphenous vein; TP receptor antagonist; TxA(2); TxS inhibitor; Vascular tone

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Saphenous Vein / Mammary Arteries Limits: Female / Humans / Male Language: En Journal: Life Sci Year: 2021 Type: Article

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