Pancreatic Acinar Cell Carcinoma with Germline BRCA2 Mutation and Severe Pancreatic Panniculitis: A Case Report.
Visc Med
; 37(5): 447-450, 2021 Oct.
Article
in En
| MEDLINE
| ID: mdl-34722729
ABSTRACT
Pancreatic acinar cell carcinoma (ACC) is a rare malignant disease that displays distinct differences to pancreatic ductal adenocarcinoma. Here, we report the case of a patient with ACC and underlying breast cancer susceptibility gene 2 (BRCA2) germline mutation that developed severe pancreatic panniculitis (PP) during the course of the disease. The patient received a multimodal therapy including surgery, systemic chemotherapy, and targeted therapy with the PARP inhibitor olaparib, resulting in an overall survival of 47 months. Findings from this case are compared to the current knowledge on management of ACC and paraneoplastic PP.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Visc Med
Year:
2021
Type:
Article
Affiliation country:
Germany