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Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency.
Bajrami, Ilirjana; Walker, Callum; Krastev, Dragomir B; Weekes, Daniel; Song, Feifei; Wicks, Andrew J; Alexander, John; Haider, Syed; Brough, Rachel; Pettitt, Stephen J; Tutt, Andrew N J; Lord, Christopher J.
Affiliation
  • Bajrami I; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Walker C; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Krastev DB; The Francis Crick Institute, London, NW1 1AT, UK.
  • Weekes D; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Song F; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Wicks AJ; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Alexander J; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Haider S; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Brough R; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Pettitt SJ; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Tutt ANJ; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Lord CJ; Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW3 6JB, UK.
Commun Biol ; 4(1): 1270, 2021 11 08.
Article in En | MEDLINE | ID: mdl-34750509
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: BRCA1 Protein / BRCA2 Protein / Sirtuins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Commun Biol Year: 2021 Type: Article Affiliation country: United kingdom
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: BRCA1 Protein / BRCA2 Protein / Sirtuins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Commun Biol Year: 2021 Type: Article Affiliation country: United kingdom