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CS1-specific single-domain antibodies labeled with Actinium-225 prolong survival and increase CD8+ T cells and PD-L1 expression in Multiple Myeloma.
De Veirman, Kim; Puttemans, Janik; Krasniqi, Ahmet; Ertveldt, Thomas; Hanssens, Heleen; Romao, Ema; Hose, Dirk; Goyvaert, Cleo; Vlummens, Philip; Muyldermans, Serge; Breckpot, Karine; Bruchertseifer, Frank; Morgenstern, Alfred; D'Huyvetter, Matthias; Devoogdt, Nick.
Affiliation
  • De Veirman K; Department of Hematology and Immunology, Vrije Universiteit Brussel, Brussels, Belgium.
  • Puttemans J; Department of Medical Imaging, Laboratory for in Vivo Cellular and Molecular Imaging, Vrije Universiteit Brussel, Brussels, Belgium.
  • Krasniqi A; Department of Medical Imaging, Laboratory for in Vivo Cellular and Molecular Imaging, Vrije Universiteit Brussel, Brussels, Belgium.
  • Ertveldt T; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium.
  • Hanssens H; Department of Medical Imaging, Laboratory for in Vivo Cellular and Molecular Imaging, Vrije Universiteit Brussel, Brussels, Belgium.
  • Romao E; Department of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium.
  • Hose D; Department of Hematology and Immunology, Vrije Universiteit Brussel, Brussels, Belgium.
  • Goyvaert C; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium.
  • Vlummens P; Department of Hematology and Immunology, Vrije Universiteit Brussel, Brussels, Belgium.
  • Muyldermans S; Department of Clinical Hematology, Ghent University Hospital, Ghent, Belgium.
  • Breckpot K; Department of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium.
  • Bruchertseifer F; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium.
  • Morgenstern A; European Commission, Joint Research Centre (JRC), Karlsruhe, Germany.
  • D'Huyvetter M; European Commission, Joint Research Centre (JRC), Karlsruhe, Germany.
  • Devoogdt N; Department of Medical Imaging, Laboratory for in Vivo Cellular and Molecular Imaging, Vrije Universiteit Brussel, Brussels, Belgium.
Oncoimmunology ; 10(1): 2000699, 2021.
Article in En | MEDLINE | ID: mdl-34777918
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Single-Domain Antibodies / Multiple Myeloma Limits: Animals / Humans Language: En Journal: Oncoimmunology Year: 2021 Type: Article Affiliation country: Belgium
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Single-Domain Antibodies / Multiple Myeloma Limits: Animals / Humans Language: En Journal: Oncoimmunology Year: 2021 Type: Article Affiliation country: Belgium