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The feasibility of using liquid biopsies as a complementary assay for copy number aberration profiling in routinely collected paediatric cancer patient samples.
Van Paemel, Ruben; Vandeputte, Charlotte; Raman, Lennart; Van Thorre, Jolien; Willems, Leen; Van Dorpe, Jo; Van Der Linden, Malaïka; De Wilde, Jilke; De Koker, Andries; Menten, Björn; Devalck, Christine; Vicha, Ales; Grega, Marek; Schleiermacher, Gudrun; Iddir, Yasmine; Chicard, Mathieu; van Zogchel, Lieke; Stutterheim, Janine; Lak, Nathalie S M; Tytgat, G A M; Laureys, Geneviève; Speleman, Frank; De Wilde, Bram; Lammens, Tim; De Preter, Katleen; Van Roy, Nadine.
Affiliation
  • Van Paemel R; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University
  • Vandeputte C; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • Raman L; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Pathology, Ghent University Hospital, Ghent, Belgium.
  • Van Thorre J; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.
  • Willems L; Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.
  • Van Dorpe J; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Pathology, Ghent University Hospital, Ghent, Belgium.
  • Van Der Linden M; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Pathology, Ghent University Hospital, Ghent, Belgium.
  • De Wilde J; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Pathology, Ghent University Hospital, Ghent, Belgium.
  • De Koker A; Center for Medical Biotechnology, Flemish Institute Biotechnology (VIB), Ghent, Belgium; Research Foundation Flanders, Belgium.
  • Menten B; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • Devalck C; Hôpital Universitaire des Enfants Reine Fabiola, Brussels, Belgium.
  • Vicha A; Department of Pediatric Hematology and Oncology, Charles University, Second Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.
  • Grega M; Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.
  • Schleiermacher G; Translational Pediatric Oncology, Centre de recherche de l'Institut Curie, Paris, France.
  • Iddir Y; Translational Pediatric Oncology, Centre de recherche de l'Institut Curie, Paris, France.
  • Chicard M; Translational Pediatric Oncology, Centre de recherche de l'Institut Curie, Paris, France.
  • van Zogchel L; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center, Amsterdam, the Netherlands.
  • Stutterheim J; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
  • Lak NSM; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center, Amsterdam, the Netherlands.
  • Tytgat GAM; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.
  • Laureys G; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.
  • Speleman F; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • De Wilde B; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.
  • Lammens T; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Pediatric Hematology, Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium.
  • De Preter K; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • Van Roy N; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium. Electronic address: Nadine.VanRoy@UGent.be.
Eur J Cancer ; 160: 12-23, 2022 01.
Article in En | MEDLINE | ID: mdl-34794856

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers, Tumor / DNA Copy Number Variations / Cell-Free Nucleic Acids / Liquid Biopsy Type of study: Observational_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Language: En Journal: Eur J Cancer Year: 2022 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers, Tumor / DNA Copy Number Variations / Cell-Free Nucleic Acids / Liquid Biopsy Type of study: Observational_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Language: En Journal: Eur J Cancer Year: 2022 Type: Article