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The Deleterious Effects of Shiga Toxin Type 2 Are Neutralized In Vitro by FabF8:Stx2 Recombinant Monoclonal Antibody.
Luz, Daniela; Gómez, Fernando D; Ferreira, Raíssa L; Melo, Bruna S; Guth, Beatriz E C; Quintilio, Wagner; Moro, Ana Maria; Presta, Agostina; Sacerdoti, Flavia; Ibarra, Cristina; Chen, Gang; Sidhu, Sachdev S; Amaral, María Marta; Piazza, Roxane M F.
Affiliation
  • Luz D; Laboratório de Bacteriologia, Instituto Butantan, Sao Paulo 05503-900, Brazil.
  • Gómez FD; Laboratorio de Fisiopatogenia, Instituto de Fisiología y Biofísica Bernardo Houssay (IFIBIO Houssay-CONICET), Departamento de Fisiología, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires 1121, Argentina.
  • Ferreira RL; Laboratório de Bacteriologia, Instituto Butantan, Sao Paulo 05503-900, Brazil.
  • Melo BS; Laboratório de Bacteriologia, Instituto Butantan, Sao Paulo 05503-900, Brazil.
  • Guth BEC; Departamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Sao Paulo, Sao Paulo 04023-062, Brazil.
  • Quintilio W; Laboratório de Biofármacos, Instituto Butantan, Sao Paulo 05503-900, Brazil.
  • Moro AM; Laboratório de Biofármacos, Instituto Butantan, Sao Paulo 05503-900, Brazil.
  • Presta A; Laboratorio de Fisiopatogenia, Instituto de Fisiología y Biofísica Bernardo Houssay (IFIBIO Houssay-CONICET), Departamento de Fisiología, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires 1121, Argentina.
  • Sacerdoti F; Laboratorio de Fisiopatogenia, Instituto de Fisiología y Biofísica Bernardo Houssay (IFIBIO Houssay-CONICET), Departamento de Fisiología, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires 1121, Argentina.
  • Ibarra C; Laboratorio de Fisiopatogenia, Instituto de Fisiología y Biofísica Bernardo Houssay (IFIBIO Houssay-CONICET), Departamento de Fisiología, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires 1121, Argentina.
  • Chen G; Banting and Best Department of Medical Research, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, OT M5S 3E1, Canada.
  • Sidhu SS; Banting and Best Department of Medical Research, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, OT M5S 3E1, Canada.
  • Amaral MM; Laboratorio de Fisiopatogenia, Instituto de Fisiología y Biofísica Bernardo Houssay (IFIBIO Houssay-CONICET), Departamento de Fisiología, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires 1121, Argentina.
  • Piazza RMF; Laboratório de Bacteriologia, Instituto Butantan, Sao Paulo 05503-900, Brazil.
Toxins (Basel) ; 13(11)2021 11 22.
Article in En | MEDLINE | ID: mdl-34822608
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin Fab Fragments / Shiga Toxin 2 / Hemolytic-Uremic Syndrome / Antibodies, Monoclonal Limits: Animals / Humans Language: En Journal: Toxins (Basel) Year: 2021 Type: Article Affiliation country: Brazil
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin Fab Fragments / Shiga Toxin 2 / Hemolytic-Uremic Syndrome / Antibodies, Monoclonal Limits: Animals / Humans Language: En Journal: Toxins (Basel) Year: 2021 Type: Article Affiliation country: Brazil