Briarane-Related Diterpenoids from Octocoral Briareum stechei.
Molecules
; 26(22)2021 Nov 13.
Article
in En
| MEDLINE
| ID: mdl-34833953
ABSTRACT
A known polyoxygenated briarane, briaexcavatolide P (1), was isolated from a Formosan octocoral Briareum stechei. Moreover, the same species B. stechei, collected from Okinawan waters, yielded three chlorine-containing briaranes, including two new compounds, briastecholides B (2) and C (3) as well as a known analogue, briarenol R (4). The structures of 1-4 were established using spectroscopic methods. In addition, briarane 1 demonstrated anti-inflammatory activity in lipo-polysaccharide-induced RAW 264.7 mouse macrophage cells by suppressing the expression of inducible nitric oxide synthase (iNOS) protein.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Anthozoa
/
Diterpenes
Limits:
Animals
Language:
En
Journal:
Molecules
Journal subject:
BIOLOGIA
Year:
2021
Type:
Article
Affiliation country:
Taiwan