Signature of long-lived memory CD8<sup>+</sup> T cells in acute SARS-CoV-2 infection.

Adamo, Sarah; Michler, Jan; Zurbuchen, Yves; Cervia, Carlo; Taeschler, Patrick; Raeber, Miro E; Baghai Sain, Simona; Nilsson, Jakob; Moor, Andreas E; Boyman, Onur

Signature of long-lived memory CD8⁺ T cells in acute SARS-CoV-2 infection.

Adamo, Sarah; Michler, Jan; Zurbuchen, Yves; Cervia, Carlo; Taeschler, Patrick; Raeber, Miro E; Baghai Sain, Simona; Nilsson, Jakob; Moor, Andreas E; Boyman, Onur.

Affiliation

Adamo S; Department of Immunology, University Hospital Zurich, Zurich, Switzerland.
Michler J; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
Zurbuchen Y; Department of Immunology, University Hospital Zurich, Zurich, Switzerland.
Cervia C; Department of Immunology, University Hospital Zurich, Zurich, Switzerland.
Taeschler P; Department of Immunology, University Hospital Zurich, Zurich, Switzerland.
Raeber ME; Department of Immunology, University Hospital Zurich, Zurich, Switzerland.
Baghai Sain S; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
Nilsson J; Department of Immunology, University Hospital Zurich, Zurich, Switzerland.
Moor AE; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
Boyman O; Department of Immunology, University Hospital Zurich, Zurich, Switzerland. onur.boyman@uzh.ch.

Nature ; 602(7895): 148-155, 2022 02.

Article in En | MEDLINE | ID: mdl-34875673

Subject(s)

Antigens, Viral/immunology; Biomarkers/metabolism; CD8-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/metabolism; COVID-19/immunology; Memory T Cells/immunology; Memory T Cells/metabolism; SARS-CoV-2/immunology; Acute Disease; COVID-19/virology; Cell Proliferation; Clone Cells/cytology; Clone Cells/immunology; Humans; Interferons/immunology; Interleukin-7 Receptor alpha Subunit/metabolism; Leukocyte Common Antigens/metabolism; Longitudinal Studies; Mechanistic Target of Rapamycin Complex 1/metabolism; Receptors, Antigen, T-Cell/metabolism; Receptors, CCR7/metabolism; T Cell Transcription Factor 1/metabolism; Time Factors; Transcriptome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers / CD8-Positive T-Lymphocytes / SARS-CoV-2 / COVID-19 / Memory T Cells / Antigens, Viral Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Nature Year: 2022 Type: Article Affiliation country: Switzerland

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