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Gain-of-Function Mutations R249C and S250C in Complement C2 Protein Increase C3 Deposition in the Presence of C-Reactive Protein.
Urban, Aleksandra; Kowalska, Daria; Stasilojc, Grzegorz; Kuzniewska, Alicja; Skrobinska, Anna; Arjona, Emilia; Alonso, Eugenia Castellote; Fenollosa Segarra, María Ángeles; Jongerius, Ilse; Spaapen, Robbert; Satchell, Simon; Thiel, Marcel; Oldziej, Stanislaw; Rodriguez de Córdoba, Santiago; Okrój, Marcin.
Affiliation
  • Urban A; Department of Cell Biology and Immunology, Intercollegiate Faculty of Biotechnology of University of Gdansk and Medical University of Gdansk, Gdansk, Poland.
  • Kowalska D; Department of Cell Biology and Immunology, Intercollegiate Faculty of Biotechnology of University of Gdansk and Medical University of Gdansk, Gdansk, Poland.
  • Stasilojc G; Department of Cell Biology and Immunology, Intercollegiate Faculty of Biotechnology of University of Gdansk and Medical University of Gdansk, Gdansk, Poland.
  • Kuzniewska A; Department of Cell Biology and Immunology, Intercollegiate Faculty of Biotechnology of University of Gdansk and Medical University of Gdansk, Gdansk, Poland.
  • Skrobinska A; Department of Cell Biology and Immunology, Intercollegiate Faculty of Biotechnology of University of Gdansk and Medical University of Gdansk, Gdansk, Poland.
  • Arjona E; Centro de Investigaciones Biológicas and Centro de Investigación Biomédica en Enfermedades Raras, Madrid, Spain.
  • Alonso EC; Servicio Nefrología, Consorci Hospitaliri de Vic, Barcelona, Spain.
  • Fenollosa Segarra MÁ; Servicio de Nefrología, Hospital General Universitario de Castellón, Castellón, Spain.
  • Jongerius I; Department of Immunopathology, Sanquin Research, Amsterdam and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
  • Spaapen R; Emma Children's Hospital, Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Amsterdam University Medical Center, Amsterdam, Netherlands.
  • Satchell S; Department of Immunopathology, Sanquin Research, Amsterdam and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
  • Thiel M; Bristol Renal, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Oldziej S; Laboratory of Biopolymers Structure, Intercollegiate Faculty of Biotechnology of University of Gdansk and Medical University of Gdansk, Gdansk, Poland.
  • Rodriguez de Córdoba S; Laboratory of Biopolymers Structure, Intercollegiate Faculty of Biotechnology of University of Gdansk and Medical University of Gdansk, Gdansk, Poland.
  • Okrój M; Centro de Investigaciones Biológicas and Centro de Investigación Biomédica en Enfermedades Raras, Madrid, Spain.
Front Immunol ; 12: 724361, 2021.
Article in En | MEDLINE | ID: mdl-34899688
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: C-Reactive Protein / Complement C2 / Complement C3 / Kidney Diseases Limits: Humans Language: En Journal: Front Immunol Year: 2021 Type: Article Affiliation country: Poland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: C-Reactive Protein / Complement C2 / Complement C3 / Kidney Diseases Limits: Humans Language: En Journal: Front Immunol Year: 2021 Type: Article Affiliation country: Poland