The role of intra and inter-molecular disulfide bonds in modulating amyloidogenesis: A review.

Mitra, Aranyak; Sarkar, Nandini

Mitra, Aranyak; Sarkar, Nandini.

Affiliation

Mitra A; Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela, 769008, Odisha, India.
Sarkar N; Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela, 769008, Odisha, India. Electronic address: sarkarn@nitrkl.ac.in.

Arch Biochem Biophys ; 716: 109113, 2022 02 15.

Article in En | MEDLINE | ID: mdl-34958750

Subject(s)

Amyloidogenic Proteins/chemistry; Amyloidosis/etiology; Disulfides/chemistry; Alzheimer Disease/etiology; Amyloidogenic Proteins/metabolism; Amyotrophic Lateral Sclerosis/etiology; Diabetes Mellitus, Type 2/etiology; Disulfides/metabolism; Humans; Insulin/chemistry; Intramolecular Lyases/chemistry; Models, Molecular; Phosphatidylinositols/metabolism; Prion Diseases/ethnology; Protein Aggregates; Protein Binding; Protein Conformation; Structure-Activity Relationship

Key words

Amyloidosis; Conformational flexibility; Disulfide bonds; Molecular interactions

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Disulfides / Amyloidogenic Proteins / Amyloidosis Type of study: Etiology_studies / Prognostic_studies Limits: Humans Language: En Journal: Arch Biochem Biophys Year: 2022 Type: Article Affiliation country: India

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