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Computational design of a neutralizing antibody with picomolar binding affinity for all concerning SARS-CoV-2 variants.
Jeong, Bo-Seong; Cha, Jeong Seok; Hwang, Insu; Kim, Uijin; Adolf-Bryfogle, Jared; Coventry, Brian; Cho, Hyun-Soo; Kim, Kyun-Do; Oh, Byung-Ha.
Affiliation
  • Jeong BS; Department of Biological Sciences, Kaist Institute for the Biocentury, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
  • Cha JS; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
  • Hwang I; Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
  • Kim U; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
  • Adolf-Bryfogle J; Institute for Protein Innovation, Boston, MA, USA.
  • Coventry B; Division of Hematology-Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
  • Cho HS; Molecular Engineering & Sciences Institute & Institute for Protein Design, University of Washington, Seattle, Washington, USA.
  • Kim KD; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
  • Oh BH; Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
MAbs ; 14(1): 2021601, 2022.
Article in En | MEDLINE | ID: mdl-35030983
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spike Glycoprotein, Coronavirus / Broadly Neutralizing Antibodies / SARS-CoV-2 / COVID-19 / Antibodies, Viral / Antigens, Viral Type of study: Health_economic_evaluation Limits: Humans Language: En Journal: MAbs Journal subject: ALERGIA E IMUNOLOGIA Year: 2022 Type: Article
Fulltext
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spike Glycoprotein, Coronavirus / Broadly Neutralizing Antibodies / SARS-CoV-2 / COVID-19 / Antibodies, Viral / Antigens, Viral Type of study: Health_economic_evaluation Limits: Humans Language: En Journal: MAbs Journal subject: ALERGIA E IMUNOLOGIA Year: 2022 Type: Article