Green and four-component cyclocondensation synthesis and in silico docking of new polyfunctionalized pyrrole derivatives as the potential anticholinesterase agents.

Meshkatalsadat, Mohammad Hadi; Mahmoudi, Ahmad; Lotfi, Safa; Pouramiri, Behjat; Foroumadi, Alireza

Meshkatalsadat, Mohammad Hadi; Mahmoudi, Ahmad; Lotfi, Safa; Pouramiri, Behjat; Foroumadi, Alireza.

Affiliation

Meshkatalsadat MH; Department of Chemistry, Faculty of Science, Qom University of Technology, 37195, Qom, Iran.
Mahmoudi A; Department of Chemistry, Shahid Bahonar University of Kerman, Kerman, Iran.
Lotfi S; Department of Biotechnology, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran.
Pouramiri B; Department of Chemistry, Faculty of Science, Qom University of Technology, 37195, Qom, Iran. b.pouramiri.chem@gmail.com.
Foroumadi A; Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. aforoumadi@yahoo.com.

Mol Divers ; 26(6): 3021-3035, 2022 Dec.

Article in En | MEDLINE | ID: mdl-35034271

Subject(s)

Cholinesterase Inhibitors; Ionic Liquids; Cholinesterase Inhibitors/chemistry; Molecular Docking Simulation; Pyrroles; Binding Sites; Ionic Liquids/chemistry; Acetylcholinesterase/metabolism; Structure-Activity Relationship; Molecular Structure

Key words

Anticholinesterase; Green synthesis; Multi-component reaction (MCRs); Polyfunctionalized pyrrole; Solvent-free conditions

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholinesterase Inhibitors / Ionic Liquids Language: En Journal: Mol Divers Journal subject: BIOLOGIA MOLECULAR Year: 2022 Type: Article Affiliation country: Iran

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