Association between vitamin D deficiency at one month of age and bronchopulmonary dysplasia.
Medicine (Baltimore)
; 100(48): e27966, 2021 Dec 03.
Article
in En
| MEDLINE
| ID: mdl-35049200
ABSTRACT
ABSTRACT Vitamin D deficiency is common and increases the likelihood of neonatal morbidities in preterm infants. This study assessed vitamin D levels at 1 month of age after 4âweeks of vitamin D supplementation and determined the association between vitamin D levels and neonatal morbidities.This retrospective study included preterm infants with birth weight <1500âg or gestational age <32âweeks born in our hospital between January 2018 and December 2019. They were administered 400 IU of oral vitamin D supplementation after birth according to our policy. The infants were then divided into sufficient (≥20âng/mL) and deficient (<20âng/mL) groups according to their serum vitamin D levels at 1 month of age.The vitamin D deficient and sufficient groups included 49 and 41 patients, respectively. The mean gestational age and birth weight. GHT in the vitamin D deficient group were 29.1â±â2.1âweeks and 1216.1â±â308.1âg, respectively, and 30.0â±â1.7âweeks and 1387.6â±â350.8âg, respectively, in the sufficient group. No significant differences were observed between the 2 groups in demographic and clinical outcomes except for bronchopulmonary dysplasia (BPD), which occurred significantly more often in the vitamin D-deficient group (odds ratio 2.21; 95% confidence interval, 1.85-2.78; Pâ=â.02).The results of our study suggest that vitamin D deficiency at 1 month of age is associated with BPD in preterm infants.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Vitamin D
/
Vitamin D Deficiency
/
Vitamins
/
Bronchopulmonary Dysplasia
Type of study:
Observational_studies
Limits:
Adult
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Female
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Humans
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Infant
/
Newborn
Language:
En
Journal:
Medicine (Baltimore)
Year:
2021
Type:
Article