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Massively parallel phenotyping of coding variants in cancer with Perturb-seq.
Ursu, Oana; Neal, James T; Shea, Emily; Thakore, Pratiksha I; Jerby-Arnon, Livnat; Nguyen, Lan; Dionne, Danielle; Diaz, Celeste; Bauman, Julia; Mosaad, Mariam Mounir; Fagre, Christian; Lo, April; McSharry, Maria; Giacomelli, Andrew O; Ly, Seav Huong; Rozenblatt-Rosen, Orit; Hahn, William C; Aguirre, Andrew J; Berger, Alice H; Regev, Aviv; Boehm, Jesse S.
Affiliation
  • Ursu O; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Neal JT; Genentech, South San Francisco, CA, USA.
  • Shea E; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Thakore PI; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Jerby-Arnon L; Department of Cancer Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Nguyen L; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Dionne D; Genentech, South San Francisco, CA, USA.
  • Diaz C; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Bauman J; Chan Zuckerberg Biohub, San Francisco, CA, USA.
  • Mosaad MM; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Fagre C; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Lo A; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • McSharry M; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Giacomelli AO; Department of Cancer Biology, Stanford University School of Medicine, Stanford, CA, USA.
  • Ly SH; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Rozenblatt-Rosen O; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Hahn WC; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Aguirre AJ; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Berger AH; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Regev A; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Boehm JS; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Nat Biotechnol ; 40(6): 896-905, 2022 06.
Article in En | MEDLINE | ID: mdl-35058622
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins p21(ras) / Lung Neoplasms Limits: Humans Language: En Journal: Nat Biotechnol Journal subject: BIOTECNOLOGIA Year: 2022 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins p21(ras) / Lung Neoplasms Limits: Humans Language: En Journal: Nat Biotechnol Journal subject: BIOTECNOLOGIA Year: 2022 Type: Article Affiliation country: United States