Vector microbiota and immunity: modulating arthropod susceptibility to vertebrate pathogens.
Curr Opin Insect Sci
; 50: 100875, 2022 04.
Article
in En
| MEDLINE
| ID: mdl-35065286
ABSTRACT
Arthropods, including mosquitoes, sand flies, tsetse flies, and ticks are vectors of many bacterial, parasitic, and viral pathogens that cause serious disease in humans and animals. Their microbiota, that is, all microorganisms that dwell within their tissues, can impact vector immunity and susceptibility to pathogen infection. Historically, host-pathogen-microbiota interactions have not been well described, with little known about mechanism. In this review, we highlight recent advances in understanding how individual microorganisms and microbial communities interact with vectors and human pathogens, the mechanisms they utilize to achieve these effects, and the potential for exploiting these interactions to control pathogen transmission. These studies fill important knowledge gaps and further our understanding of the roles that the vector microbiota plays in pathogen transmission.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Arthropods
/
Microbiota
Limits:
Animals
Language:
En
Journal:
Curr Opin Insect Sci
Year:
2022
Type:
Article
Affiliation country:
United States