Hypertrophic Cardiomyopathy: New Concepts and Therapies.
Annu Rev Med
; 73: 363-375, 2022 01 27.
Article
in En
| MEDLINE
| ID: mdl-35084989
ABSTRACT
Hypertrophic cardiomyopathy (HCM), a relatively common, globally distributed, and often inherited myocardial disorder, transformed over the last several years into a treatable condition with the emergence of effective management options that alter natural history at all ages. Now available are a matured risk stratification algorithm selecting patients for prophylactic implantable defibrillators that prevent arrhythmic sudden death; low-risk, high-benefit surgical myectomy to reverse progressive heart failure symptoms due to left ventricular outflow obstruction; anticoagulation prophylaxis to prevent atrial fibrillation-mediated embolic stroke; and heart transplant for refractory end-stage disease in the absence of obstruction. Those strategies have resulted in reduction of HCM-related morbidity and reduction of mortality to 0.5% per year.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Atrial Fibrillation
/
Cardiomyopathy, Hypertrophic
/
Defibrillators, Implantable
Limits:
Humans
Language:
En
Journal:
Annu Rev Med
Year:
2022
Type:
Article