Serum RNAs can predict lung cancer up to 10 years prior to diagnosis.

Umu, Sinan U; Langseth, Hilde; Zuber, Verena; Helland, Åslaug; Lyle, Robert; Rounge, Trine B

Umu, Sinan U; Langseth, Hilde; Zuber, Verena; Helland, Åslaug; Lyle, Robert; Rounge, Trine B.

Affiliation

Umu SU; Department of Research, Cancer Registry of Norway, Oslo, Norway.
Langseth H; Department of Research, Cancer Registry of Norway, Oslo, Norway.
Zuber V; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom.
Helland Å; Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom.
Lyle R; Department of Oncology, Oslo University Hospital, Oslo, Norway.
Rounge TB; Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.

Elife ; 112022 02 11.

Article in En | MEDLINE | ID: mdl-35147498

Subject(s)

Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; MicroRNAs; RNA, Neoplasm; Biomarkers, Tumor/blood; Biomarkers, Tumor/genetics; Carcinoma, Non-Small-Cell Lung/blood; Carcinoma, Non-Small-Cell Lung/genetics; Early Detection of Cancer; Humans; Lung Neoplasms/blood; Lung Neoplasms/diagnosis; Lung Neoplasms/genetics; Lung Neoplasms/pathology; MicroRNAs/blood; MicroRNAs/genetics; RNA, Neoplasm/blood; RNA, Neoplasm/genetics; ROC Curve

Key words

RNA; biomarker; cancer biology; human; human serum; lung cancer; prediagnostic samples

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Neoplasm / Carcinoma, Non-Small-Cell Lung / MicroRNAs / Lung Neoplasms Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Humans Language: En Journal: Elife Year: 2022 Type: Article Affiliation country: Norway

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