Lactobacillus reuteri-an old acquaintance takes on a new task in colorectal tumor surveillance.
Cancer Cell
; 40(2): 125-127, 2022 02 14.
Article
in En
| MEDLINE
| ID: mdl-35167822
ABSTRACT
In this issue of Cancer Cell, Bell et al. identify the commensal bacterium Lactobacillus reuteri and its major metabolite reuterin as an important gatekeeper and promising target in colorectal cancerogenesis. They decipher a metabolic interplay in which L. reuteri is suppressed by metabolites from dysplastic intestinal epithelial cells which in turn are highly sensitive to the oxidative effects of the electrophile reuterin.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Colorectal Neoplasms
/
Limosilactobacillus reuteri
Type of study:
Screening_studies
Limits:
Humans
Language:
En
Journal:
Cancer Cell
Journal subject:
NEOPLASIAS
Year:
2022
Type:
Article