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In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model.
Noh, Byunghwa; Rim, John Hoon; Gopalappa, Ramu; Lin, Haiyue; Kim, Kyu Min; Kang, Min Jin; Gee, Heon Yung; Choi, Jae Young; Kim, Hyongbum Henry; Jung, Jinsei.
Affiliation
  • Noh B; Department of Otorhinolaryngology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
  • Rim JH; Institute for Yonsei Ear Science, Seoul 03722, Republic of Korea.
  • Gopalappa R; Institute for Yonsei Ear Science, Seoul 03722, Republic of Korea.
  • Lin H; Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
  • Kim KM; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
  • Kang MJ; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
  • Gee HY; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
  • Choi JY; Department of Otorhinolaryngology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
  • Kim HH; Institute for Yonsei Ear Science, Seoul 03722, Republic of Korea.
  • Jung J; Department of Otorhinolaryngology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Theranostics ; 12(5): 2465-2482, 2022.
Article in En | MEDLINE | ID: mdl-35265220
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Editing / Hearing Loss Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Theranostics Year: 2022 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Editing / Hearing Loss Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Theranostics Year: 2022 Type: Article