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Particulate levodopa nose-to-brain delivery targets dopamine to the brain with no plasma exposure.
Dimiou, Savvas; Lopes, Rui M; Kubajewska, Ilona; Mellor, Ryan D; Schlosser, Corinna S; Shet, Manjunath S; Huang, Hugh; Akcan, Ozgur; Whiteside, Garth T; Schätzlein, Andreas G; Uchegbu, Ijeoma F.
Affiliation
  • Dimiou S; UCL School of Pharmacy, 29-39 Brunswick Square, London WC1N 1AX, UK; Nanomerics Ltd., 6th Floor, 2 London Wall Place, London EC2Y 5AU, UK.
  • Lopes RM; UCL School of Pharmacy, 29-39 Brunswick Square, London WC1N 1AX, UK; Nanomerics Ltd., 6th Floor, 2 London Wall Place, London EC2Y 5AU, UK.
  • Kubajewska I; UCL School of Pharmacy, 29-39 Brunswick Square, London WC1N 1AX, UK; Nanomerics Ltd., 6th Floor, 2 London Wall Place, London EC2Y 5AU, UK.
  • Mellor RD; UCL School of Pharmacy, 29-39 Brunswick Square, London WC1N 1AX, UK; Nanomerics Ltd., 6th Floor, 2 London Wall Place, London EC2Y 5AU, UK.
  • Schlosser CS; UCL School of Pharmacy, 29-39 Brunswick Square, London WC1N 1AX, UK; Nanomerics Ltd., 6th Floor, 2 London Wall Place, London EC2Y 5AU, UK.
  • Shet MS; Imbrium Therapeutics, One Stamford Forum, 201 Tresser Blvd., Stamford, CT 06901, USA.
  • Huang H; Imbrium Therapeutics, One Stamford Forum, 201 Tresser Blvd., Stamford, CT 06901, USA.
  • Akcan O; Imbrium Therapeutics, One Stamford Forum, 201 Tresser Blvd., Stamford, CT 06901, USA.
  • Whiteside GT; Imbrium Therapeutics, One Stamford Forum, 201 Tresser Blvd., Stamford, CT 06901, USA.
  • Schätzlein AG; UCL School of Pharmacy, 29-39 Brunswick Square, London WC1N 1AX, UK; Nanomerics Ltd., 6th Floor, 2 London Wall Place, London EC2Y 5AU, UK.
  • Uchegbu IF; UCL School of Pharmacy, 29-39 Brunswick Square, London WC1N 1AX, UK; Nanomerics Ltd., 6th Floor, 2 London Wall Place, London EC2Y 5AU, UK. Electronic address: ijeoma.uchegbu@ucl.ac.uk.
Int J Pharm ; 618: 121658, 2022 Apr 25.
Article in En | MEDLINE | ID: mdl-35292396
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Levodopa Limits: Animals Language: En Journal: Int J Pharm Year: 2022 Type: Article Affiliation country: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Levodopa Limits: Animals Language: En Journal: Int J Pharm Year: 2022 Type: Article Affiliation country: United kingdom