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Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19.
Wong, Lok-Yin Roy; Zheng, Jian; Wilhelmsen, Kevin; Li, Kun; Ortiz, Miguel E; Schnicker, Nicholas J; Thurman, Andrew; Pezzulo, Alejandro A; Szachowicz, Peter J; Li, Pengfei; Pan, Ruangang; Klumpp, Klaus; Aswad, Fred; Rebo, Justin; Narumiya, Shuh; Murakami, Makoto; Zuniga, Sonia; Sola, Isabel; Enjuanes, Luis; Meyerholz, David K; Fortney, Kristen; McCray, Paul B; Perlman, Stanley.
Affiliation
  • Wong LR; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
  • Zheng J; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
  • Wilhelmsen K; BIOAGE Labs, Richmond, CA, USA.
  • Li K; Department of Pediatrics, University of Iowa, Iowa City, IA, USA.
  • Ortiz ME; Department of Pediatrics, University of Iowa, Iowa City, IA, USA.
  • Schnicker NJ; Protein and Crystallography Facility, University of Iowa, Iowa City, IA, USA.
  • Thurman A; Department Internal Medicine, University of Iowa, Iowa City, IA, USA.
  • Pezzulo AA; Department Internal Medicine, University of Iowa, Iowa City, IA, USA.
  • Szachowicz PJ; Department Internal Medicine, University of Iowa, Iowa City, IA, USA.
  • Li P; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
  • Pan R; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA.
  • Klumpp K; BIOAGE Labs, Richmond, CA, USA.
  • Aswad F; BIOAGE Labs, Richmond, CA, USA.
  • Rebo J; BIOAGE Labs, Richmond, CA, USA.
  • Narumiya S; Department of Drug Discovery Medicine, Kyoto University, Kyoto, Japan.
  • Murakami M; Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Zuniga S; Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.
  • Sola I; Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.
  • Enjuanes L; Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.
  • Meyerholz DK; Department of Pathology, University of Iowa, Iowa City, IA, USA.
  • Fortney K; BIOAGE Labs, Richmond, CA, USA.
  • McCray PB; Department of Microbiology and Immunology, University of Iowa, Iowa City, IA, USA. paul-mccray@uiowa.edu.
  • Perlman S; Department of Pediatrics, University of Iowa, Iowa City, IA, USA. paul-mccray@uiowa.edu.
Nature ; 605(7908): 146-151, 2022 05.
Article in En | MEDLINE | ID: mdl-35314834
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Animals Language: En Journal: Nature Year: 2022 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Animals Language: En Journal: Nature Year: 2022 Type: Article Affiliation country: United States