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Simultaneous Genetic Ablation of PD-1, LAG-3, and TIM-3 in CD8 T Cells Delays Tumor Growth and Improves Survival Outcome.
Ciraolo, Elisa; Althoff, Stefanie; Ruß, Josefine; Rosnev, Stanislav; Butze, Monique; Pühl, Miriam; Frentsch, Marco; Bullinger, Lars; Na, Il-Kang.
Affiliation
  • Ciraolo E; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité Universitätsmedizin Berlin, 13125 Berlin, Germany.
  • Althoff S; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité Universitätsmedizin Berlin, 13125 Berlin, Germany.
  • Ruß J; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité Universitätsmedizin Berlin, 13125 Berlin, Germany.
  • Rosnev S; Department of Hematology, Oncology and Tumor Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.
  • Butze M; Berlin Institute of Health Center for Regenerative Therapies, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.
  • Pühl M; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité Universitätsmedizin Berlin, 13125 Berlin, Germany.
  • Frentsch M; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité Universitätsmedizin Berlin, 13125 Berlin, Germany.
  • Bullinger L; Department of Hematology, Oncology and Tumor Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 10117 Berlin, Germany.
  • Na IK; Berlin Institute of Health Center for Regenerative Therapies, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.
Int J Mol Sci ; 23(6)2022 Mar 16.
Article in En | MEDLINE | ID: mdl-35328630
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Programmed Cell Death 1 Receptor / Neoplasms Limits: Humans Language: En Journal: Int J Mol Sci Year: 2022 Type: Article Affiliation country: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Programmed Cell Death 1 Receptor / Neoplasms Limits: Humans Language: En Journal: Int J Mol Sci Year: 2022 Type: Article Affiliation country: Germany