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Oridonin alleviates hyperbilirubinemia through activating LXRα-UGT1A1 axis.
Zhan, Zhikun; Dai, Fahong; Zhang, Tao; Chen, Yulian; She, Jianglian; Jiang, Huanguo; Liu, Shuwen; Gu, Tanwei; Tang, Lan.
Affiliation
  • Zhan Z; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
  • Dai F; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
  • Zhang T; Department of Pharmaceutical, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong 510623, China.
  • Chen Y; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
  • She J; CAS Key Laboratory of Tropical Marine Bioresources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
  • Jiang H; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
  • Liu S; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; State Key Laboratory of Organ Failure Research, Southern Medical University, Guangzh
  • Gu T; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.
  • Tang L; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China; State Key Laboratory of Organ Failure Research, Southern Medical University, Guangzh
Pharmacol Res ; 178: 106188, 2022 04.
Article in En | MEDLINE | ID: mdl-35338002
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bilirubin / Hyperbilirubinemia Limits: Animals Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2022 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bilirubin / Hyperbilirubinemia Limits: Animals Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2022 Type: Article Affiliation country: China