Protection of bacteriophage-sensitive Escherichia coli by lysogens.
Proc Natl Acad Sci U S A
; 119(14): e2106005119, 2022 04 05.
Article
in En
| MEDLINE
| ID: mdl-35344423
ABSTRACT
SignificanceSome viruses that infect bacteria, temperate bacteriophages, can confer immunity to infection by the same virus. Here we report λ-immune bacteria could protect λ-sensitive bacteria from killing by phage λ in mixed culture. The protection depended on the extent to which the immune bacteria were able to adsorb the phage. Reconciling modeling with experiment led to identifying a decline in protection as bacteria stopped growing. Adsorption of λ was compromised by inhibition of bacterial energy metabolism, explaining the loss of protection as bacterial growth ceased.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bacteriophages
Type of study:
Diagnostic_studies
Language:
En
Journal:
Proc Natl Acad Sci U S A
Year:
2022
Type:
Article
Affiliation country:
Denmark