Neoadjuvant Therapy for Rectal Cancer.
Surg Oncol Clin N Am
; 31(2): 279-291, 2022 04.
Article
in En
| MEDLINE
| ID: mdl-35351278
ABSTRACT
The treatment of locally advanced rectal cancer is challenging and requires a multidisciplinary approach. Neoadjuvant treatment has improved local control by the combination of radiotherapy, surgery, and chemotherapy. However, neoadjuvant treatment has not yet been shown to improve overall survival and is associated with toxicities and late sequelae that impair the quality of life of patients. Currently, different types of neoadjuvant strategies have raised the question about which one is the optimal strategy for rectal cancer treatment. In this article, we explore the different neoadjuvant treatment regimens currently available, their associated benefits and toxicities, and novel approaches in this area.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Rectal Neoplasms
/
Neoadjuvant Therapy
Limits:
Humans
Language:
En
Journal:
Surg Oncol Clin N Am
Journal subject:
NEOPLASIAS
Year:
2022
Type:
Article