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Worse Prognosis in the Symptomatic Patients With Lung Cancer - Czech Multicentric Study.
Marel, Miloslav; Chladkova, Zdenka; Casas Mendez, Luis Fernando; Venclicek, Ondrej; Skrickova, Jana; Fischer, Ondej; Mullerova, Andrea; Havel, Libor; Gyorfy, Zuzana; Hrnciarik, Michal; Jirousek, Michal; Krejci, Jana; Krejci, Daniel; Buresova, Marcela; Alahakoon, Jana; Svoboda, Michal; Svaton, Martin.
Affiliation
  • Marel M; Department of Pulmonology, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
  • Chladkova Z; Department of Pulmonology, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
  • Casas Mendez LF; Department of Pulmonology, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic.
  • Venclicek O; Department of Respiratory Diseases, Faculty of Medicine, Masaryk University, University Hospital, Brno, Czech Republic.
  • Skrickova J; Department of Respiratory Diseases, Faculty of Medicine, Masaryk University, University Hospital, Brno, Czech Republic.
  • Fischer O; Department of Respiratory Medicine, University Hospital, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Mullerova A; Department of Respiratory Medicine, University Hospital, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.
  • Havel L; Department of Respiratory Medicine, Thomayer Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Gyorfy Z; Department of Respiratory Medicine, Thomayer Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Hrnciarik M; Pulmonary Department, University Hospital, Charles University, Faculty of Medicine, Hradec Kralove, Czech Republic.
  • Jirousek M; Pulmonary Department, University Hospital, Charles University, Faculty of Medicine, Hradec Kralove, Czech Republic.
  • Krejci J; Department of Pneumology, Bulovka University Hospital, 3rd Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Krejci D; Department of Pneumology, Bulovka University Hospital, 3rd Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Buresova M; Department of Pneumology and Phthiseology, University Hospital, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.
  • Alahakoon J; OAKS Consulting Praha, Prague, Czech Republic.
  • Svoboda M; Institute of Biostatistics and Analyses, Ltd., Brno, Czech Republic.
  • Svaton M; Department of Pneumology and Phthiseology, University Hospital, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic.
Cancer Diagn Progn ; 2(2): 167-172, 2022.
Article in En | MEDLINE | ID: mdl-35399169
ABSTRACT
Background/

Aim:

This study aimed at contributing to a better diagnosis of lung cancer by analyzing the patient's symptoms and their linkage to other characteristics. Patients and

Methods:

We analyzed the data of 3,322 patients from LUCAS (LUngCAncerfocuS) National Registry of the Czech Republic. Overall survival was assessed using the Kaplan-Meier method.

Results:

The most common symptoms were cough (47.5%), dyspnea (45.6%), pain (27.3%), and weight loss (25.7%). Among all patients, 16% were asymptomatic. We demonstrated the negative prognostic significance of increasing number of lung cancer symptoms, that was significant after adjustment for age, TNM stages, and performance status, and morphological types of the cancer.

Conclusion:

Monitoring the severity and type of symptoms in patients with lung cancer can help in the diagnostics of the disease and the estimation of prognosis.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Language: En Journal: Cancer Diagn Progn Year: 2022 Type: Article Affiliation country: Czech Republic
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Language: En Journal: Cancer Diagn Progn Year: 2022 Type: Article Affiliation country: Czech Republic