High-throughput design of symmetrical dimeric SARS-CoV-2 main protease: structural and physical insights into hotspots for adaptation and therapeutics.

Padhi, Aditya K; Tripathi, Timir

Padhi, Aditya K; Tripathi, Timir.

Affiliation

Padhi AK; Laboratory for Structural Bioinformatics, Center for Biosystems Dynamics Research, RIKEN, Yokohama, Kanagawa 230-0045, Japan. adityapadhi.iitd@gmail.com.
Tripathi T; Molecular and Structural Biophysics Laboratory, Department of Biochemistry, North-Eastern Hill University, Shillong - 793022, India. timir.tripathi@gmail.com.

Phys Chem Chem Phys ; 24(16): 9141-9145, 2022 Apr 20.

Article in En | MEDLINE | ID: mdl-35411366

Subject(s)

Coronavirus 3C Proteases; Protein Engineering; SARS-CoV-2; COVID-19; Coronavirus 3C Proteases/genetics; Dimerization; Humans; SARS-CoV-2/enzymology; SARS-CoV-2/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Engineering / Coronavirus 3C Proteases / SARS-CoV-2 Limits: Humans Language: En Journal: Phys Chem Chem Phys Journal subject: BIOFISICA / QUIMICA Year: 2022 Type: Article Affiliation country: Japan

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