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Uncoupling immune trajectories of response and adverse events from anti-PD-1 immunotherapy in hepatocellular carcinoma.
Chuah, Samuel; Lee, Joycelyn; Song, Yuan; Kim, Hyung-Don; Wasser, Martin; Kaya, Neslihan A; Bang, Kyunghye; Lee, Yong Joon; Jeon, Seung Hyuck; Suthen, Sheena; A'Azman, Shamirah; Gien, Gerald; Lim, Chun Jye; Chua, Camillus; Hazirah, Sharifah Nur; Lee, Hong Kai; Lim, Jia Qi; Lim, Tony K H; Yeong, Joe; Chen, Jinmiao; Shin, Eui-Cheol; Albani, Salvatore; Zhai, Weiwei; Yoo, Changhoon; Liu, Haiyan; Choo, Su Pin; Tai, David; Chew, Valerie.
Affiliation
  • Chuah S; Translational Immunology Institute (TII), SingHealth-DukeNUS Academic Medical Centre, Singapore 169856, Singapore.
  • Lee J; Division of Medical Oncology, National Cancer Centre Singapore, Singapore 169610, Singapore.
  • Song Y; Immunology Programme, Life Sciences Institute, Immunology Translational Research Program and Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117456, Singapore.
  • Kim HD; Department of Oncology, Asan Medical Center (AMC), University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea.
  • Wasser M; Translational Immunology Institute (TII), SingHealth-DukeNUS Academic Medical Centre, Singapore 169856, Singapore; Duke-NUS Medical School, Singapore 169857, Singapore.
  • Kaya NA; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A∗STAR), Singapore 138672, Singapore; School of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore.
  • Bang K; Department of Oncology, Asan Medical Center (AMC), University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea.
  • Lee YJ; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.
  • Jeon SH; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.
  • Suthen S; Translational Immunology Institute (TII), SingHealth-DukeNUS Academic Medical Centre, Singapore 169856, Singapore.
  • A'Azman S; Translational Immunology Institute (TII), SingHealth-DukeNUS Academic Medical Centre, Singapore 169856, Singapore.
  • Gien G; Translational Immunology Institute (TII), SingHealth-DukeNUS Academic Medical Centre, Singapore 169856, Singapore.
  • Lim CJ; Translational Immunology Institute (TII), SingHealth-DukeNUS Academic Medical Centre, Singapore 169856, Singapore.
  • Chua C; Translational Immunology Institute (TII), SingHealth-DukeNUS Academic Medical Centre, Singapore 169856, Singapore.
  • Hazirah SN; Translational Immunology Institute (TII), SingHealth-DukeNUS Academic Medical Centre, Singapore 169856, Singapore.
  • Lee HK; Singapore Immunology Network (SIgN), A∗STAR, Singapore 138648, Singapore.
  • Lim JQ; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A∗STAR), Singapore 138672, Singapore.
  • Lim TKH; Duke-NUS Medical School, Singapore 169857, Singapore; Department of Anatomical Pathology, Singapore General Hospital (SGH), Singapore 169856, Singapore.
  • Yeong J; Duke-NUS Medical School, Singapore 169857, Singapore; Department of Anatomical Pathology, Singapore General Hospital (SGH), Singapore 169856, Singapore; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.
  • Chen J; Singapore Immunology Network (SIgN), A∗STAR, Singapore 138648, Singapore.
  • Shin EC; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.
  • Albani S; Translational Immunology Institute (TII), SingHealth-DukeNUS Academic Medical Centre, Singapore 169856, Singapore; Duke-NUS Medical School, Singapore 169857, Singapore.
  • Zhai W; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A∗STAR), Singapore 138672, Singapore; Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing 100107, China; Center for Excellence in Animal Evolution an
  • Yoo C; Department of Oncology, Asan Medical Center (AMC), University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea.
  • Liu H; Immunology Programme, Life Sciences Institute, Immunology Translational Research Program and Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117456, Singapore.
  • Choo SP; Division of Medical Oncology, National Cancer Centre Singapore, Singapore 169610, Singapore; Curie Oncology, Mount Elizabeth Novena Specialist Centre, Singapore 329563, Singapore.
  • Tai D; Division of Medical Oncology, National Cancer Centre Singapore, Singapore 169610, Singapore. Electronic address: david.tai.w.m@singhealth.com.sg.
  • Chew V; Translational Immunology Institute (TII), SingHealth-DukeNUS Academic Medical Centre, Singapore 169856, Singapore; Duke-NUS Medical School, Singapore 169857, Singapore. Electronic address: valerie.chew@duke-nus.edu.sg.
J Hepatol ; 77(3): 683-694, 2022 09.
Article in En | MEDLINE | ID: mdl-35430299
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Liver Neoplasms Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2022 Type: Article Affiliation country: Singapore
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Liver Neoplasms Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2022 Type: Article Affiliation country: Singapore