Validating the Mild Behavioral Impairment Checklist in a Cognitive Clinic: Comparisons With the Neuropsychiatric Inventory Questionnaire.
J Geriatr Psychiatry Neurol
; 36(2): 107-120, 2023 03.
Article
in En
| MEDLINE
| ID: mdl-35430902
ABSTRACT
OBJECTIVE:
To compare the utility of the Mild Behavioral Impairment-Checklist (MBI-C) and Neuropsychiatric Inventory Questionnaire (NPI-Q) to capture NPS in subjective cognitive decline (SCD), mild cognitive impairment (MCI), and dementia.METHODS:
In this cross-sectional memory clinic study, linear regression models compared MBI-C (n = 474) and NPI-Q (n = 1040) scores in relation to Montreal Cognitive Assessment (MoCA) score.RESULTS:
MBI prevalence was 37% in subjective cognitive decline, 54% in mild cognitive impairment, and 62% in dementia. Worse diagnostic status was associated with higher MBI-C and NPI-Q score (P < .001), lower MoCA (P < .001), and greater age (P < .001). Higher MBI-C (ß -.09; 95% CI -.13, -.05) and NPI-Q (ß -.17; 95% CI -.23, -.10) scores were associated with lower MoCA scores, with psychosis most strongly associated (ß -1.11; 95% CI -1.56, -.65 vs ß -1.14; 95% CI -1.55, -.73).CONCLUSIONS:
The MBI-C captures global and domain-specific NPS across cognitive stages. Both the MBI-C and NPI-Q have utility in characterizing NPS.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dementia
/
Cognitive Dysfunction
Type of study:
Prognostic_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
J Geriatr Psychiatry Neurol
Journal subject:
GERIATRIA
/
NEUROLOGIA
/
PSIQUIATRIA
Year:
2023
Type:
Article
Affiliation country:
Canada