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Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax.
Hodder, Anthony N; Christensen, Janni; Scally, Stephen; Triglia, Tony; Ngo, Anna; Birkinshaw, Richard W; Bailey, Brodie; Favuzza, Paola; Dietrich, Melanie H; Tham, Wai-Hong; Czabotar, Peter E; Lowes, Kym; Guo, Zhuyan; Murgolo, Nicholas; Lera Ruiz, Manuel de; McCauley, John A; Sleebs, Brad E; Olsen, David; Cowman, Alan F.
Affiliation
  • Hodder AN; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia; University of Melbourne, Melbourne, 3010 VIC, Australia.
  • Christensen J; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia; University of Melbourne, Melbourne, 3010 VIC, Australia.
  • Scally S; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia; University of Melbourne, Melbourne, 3010 VIC, Australia.
  • Triglia T; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia.
  • Ngo A; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia.
  • Birkinshaw RW; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia; University of Melbourne, Melbourne, 3010 VIC, Australia.
  • Bailey B; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia; University of Melbourne, Melbourne, 3010 VIC, Australia.
  • Favuzza P; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia; University of Melbourne, Melbourne, 3010 VIC, Australia.
  • Dietrich MH; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia; University of Melbourne, Melbourne, 3010 VIC, Australia.
  • Tham WH; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia; University of Melbourne, Melbourne, 3010 VIC, Australia.
  • Czabotar PE; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia; University of Melbourne, Melbourne, 3010 VIC, Australia.
  • Lowes K; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia.
  • Guo Z; Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Murgolo N; Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Lera Ruiz M; Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • McCauley JA; Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Sleebs BE; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia; University of Melbourne, Melbourne, 3010 VIC, Australia.
  • Olsen D; Merck & Co., Inc, 770 Sumneytown Pike, West Point, PA 19486, USA.
  • Cowman AF; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052 VIC, Australia; University of Melbourne, Melbourne, 3010 VIC, Australia. Electronic address: cowman@wehi.edu.au.
Structure ; 30(7): 947-961.e6, 2022 07 07.
Article in En | MEDLINE | ID: mdl-35460613
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Aspartic Acid Endopeptidases Language: En Journal: Structure Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Year: 2022 Type: Article Affiliation country: Australia
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Aspartic Acid Endopeptidases Language: En Journal: Structure Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Year: 2022 Type: Article Affiliation country: Australia