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Childhood body size directly increases type 1 diabetes risk based on a lifecourse Mendelian randomization approach.
Richardson, Tom G; Crouch, Daniel J M; Power, Grace M; Morales-Berstein, Fernanda; Hazelwood, Emma; Fang, Si; Cho, Yoonsu; Inshaw, Jamie R J; Robertson, Catherine C; Sidore, Carlo; Cucca, Francesco; Rich, Steven S; Todd, John A; Davey Smith, George.
Affiliation
  • Richardson TG; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, United Kingdom. Tom.G.Richardson@bristol.ac.uk.
  • Crouch DJM; Novo Nordisk Research Centre Oxford, Old Road Campus, Oxford, United Kingdom. Tom.G.Richardson@bristol.ac.uk.
  • Power GM; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.
  • Morales-Berstein F; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, United Kingdom.
  • Hazelwood E; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, United Kingdom.
  • Fang S; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, United Kingdom.
  • Cho Y; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, United Kingdom.
  • Inshaw JRJ; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, United Kingdom.
  • Robertson CC; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.
  • Sidore C; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, United States.
  • Cucca F; Institute for Research in Genetics and Biomedicine (IRGB), Sardinia, Italy.
  • Rich SS; Institute for Research in Genetics and Biomedicine (IRGB), Sardinia, Italy.
  • Todd JA; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, United States.
  • Davey Smith G; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.
Nat Commun ; 13(1): 2337, 2022 04 28.
Article in En | MEDLINE | ID: mdl-35484151
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 1 / Pediatric Obesity Type of study: Clinical_trials / Etiology_studies / Risk_factors_studies / Systematic_reviews Limits: Adult / Child / Humans / Newborn Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Type: Article Affiliation country: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 1 / Pediatric Obesity Type of study: Clinical_trials / Etiology_studies / Risk_factors_studies / Systematic_reviews Limits: Adult / Child / Humans / Newborn Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Type: Article Affiliation country: United kingdom