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Lyophilized Filovirus Glycoprotein Vaccines: Peroxides in a Vaccine Formulation with Polysorbate 80-Containing Adjuvant are Associated with Reduced Neutralizing Antibody Titers in Both Mice and Non-Human Primates.
Preston, Kendall B; Wong, Teri Ann S; Lieberman, Michael M; To, Albert; Lai, Chih-Yun; Granados, Alex; Thomasson, Holly; Misamore, John; Yalley-Ogunro, Jake; Cabus, Mehtap; Andersen, Hanne; Donini, Oreola; Lehrer, Axel T; Randolph, Theodore W.
Affiliation
  • Preston KB; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO 80303, United States.
  • Wong TAS; Department of Tropical Medicine, Medical Microbiology & Pharmacology, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI 96813, United States.
  • Lieberman MM; Department of Tropical Medicine, Medical Microbiology & Pharmacology, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI 96813, United States.
  • To A; Department of Tropical Medicine, Medical Microbiology & Pharmacology, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI 96813, United States.
  • Lai CY; Department of Tropical Medicine, Medical Microbiology & Pharmacology, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI 96813, United States.
  • Granados A; BIOQUAL, Inc., Rockville, MD 20850, United States.
  • Thomasson H; BIOQUAL, Inc., Rockville, MD 20850, United States.
  • Misamore J; BIOQUAL, Inc., Rockville, MD 20850, United States.
  • Yalley-Ogunro J; BIOQUAL, Inc., Rockville, MD 20850, United States.
  • Cabus M; BIOQUAL, Inc., Rockville, MD 20850, United States.
  • Andersen H; BIOQUAL, Inc., Rockville, MD 20850, United States.
  • Donini O; Soligenix, Inc., Princeton, NJ 08540, United States.
  • Lehrer AT; Department of Tropical Medicine, Medical Microbiology & Pharmacology, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI 96813, United States.
  • Randolph TW; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO 80303, United States. Electronic address: Theodore.randolph@colorado.edu.
J Pharm Sci ; 111(12): 3424-3434, 2022 12.
Article in En | MEDLINE | ID: mdl-35609629
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Vaccines / Ebolavirus Type of study: Risk_factors_studies Limits: Animals Language: En Journal: J Pharm Sci Year: 2022 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Vaccines / Ebolavirus Type of study: Risk_factors_studies Limits: Animals Language: En Journal: J Pharm Sci Year: 2022 Type: Article Affiliation country: United States