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Application of empirical scalars to enable early prediction of human hepatic clearance using IVIVE in drug discovery: an evaluation of 173 drugs.
Jones, Robert S; Leung, Christian; Chang, Jae H; Brown, Suzanne; Liu, Ning; Yan, Zhengyin; Kenny, Jane R; Broccatelli, Fabio.
Affiliation
  • Jones RS; Genentech, Inc, United States jones.robert@gene.com.
  • Leung C; Genentech, United States.
  • Chang JH; Preclinical Development Sciences, ORIC Pharmaceuticals, United States.
  • Brown S; Ultragenyx Pharmaceutical, United States.
  • Liu N; Avirmax, Inc., United States.
  • Yan Z; DMPK, Genentech INC, United States.
  • Kenny JR; Drug Metabolism & Pharmacokinetics, Genentech Inc, United States.
  • Broccatelli F; Genentech, United States.
Drug Metab Dispos ; 2022 May 30.
Article in En | MEDLINE | ID: mdl-35636770
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2022 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2022 Type: Article Affiliation country: United States