Coming in from the cold: overcoming the hostile immune microenvironment of medulloblastoma.

Eisemann, Tanja; Wechsler-Reya, Robert J

Eisemann, Tanja; Wechsler-Reya, Robert J.

Affiliation

Eisemann T; Tumor Initiation and Maintenance Program, National Cancer Institute-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California 92037, USA.
Wechsler-Reya RJ; Tumor Initiation and Maintenance Program, National Cancer Institute-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California 92037, USA.

Genes Dev ; 36(9-10): 514-532, 2022 05 01.

Article in En | MEDLINE | ID: mdl-35680424

Subject(s)

Brain Neoplasms; Cerebellar Neoplasms; Medulloblastoma; Cerebellar Neoplasms/genetics; Cerebellar Neoplasms/therapy; Child; Humans; Immunotherapy; Medulloblastoma/therapy; Tumor Microenvironment

Key words

CAR T cell; antigen presentation; immune checkpoint; immunotherapy; medulloblastoma; myeloid cell; oncolytic virus; pediatric brain tumor; vaccination

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Cerebellar Neoplasms / Medulloblastoma Limits: Child / Humans Language: En Journal: Genes Dev Journal subject: BIOLOGIA MOLECULAR Year: 2022 Type: Article Affiliation country: United States

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