GH Responsiveness Is not Correlated to <i>IGF1</i> P2 Promoter Methylation in Children With Turner Syndrome, GHD and SGA Short Stature.

Apel, Anja; Iliev, Daniel I; Urban, Christina; Weber, Karin; Schweizer, Roland; Blumenstock, Gunnar; Pasche, Sarah; Nieratschker, Vanessa; Binder, Gerhard

GH Responsiveness Is not Correlated to IGF1 P2 Promoter Methylation in Children With Turner Syndrome, GHD and SGA Short Stature.

Apel, Anja; Iliev, Daniel I; Urban, Christina; Weber, Karin; Schweizer, Roland; Blumenstock, Gunnar; Pasche, Sarah; Nieratschker, Vanessa; Binder, Gerhard.

Affiliation

Apel A; Pediatric Endocrinology, University Children`s Hospital Tübingen, Tübingen, Germany.
Iliev DI; Pediatric Endocrinology, University Children`s Hospital Tübingen, Tübingen, Germany.
Urban C; Pediatric Endocrinology, University Children`s Hospital Tübingen, Tübingen, Germany.
Weber K; Pediatric Endocrinology, University Children`s Hospital Tübingen, Tübingen, Germany.
Schweizer R; Pediatric Endocrinology, University Children`s Hospital Tübingen, Tübingen, Germany.
Blumenstock G; Department of Clinical Epidemiology and Applied Biometry, University of Tübingen, Tübingen, Germany.
Pasche S; Department of Psychiatry and Psychotherapy, Tübingen Center for Mental Health, University Hospital Tübingen, Tübingen, Germany.
Nieratschker V; Department of Psychiatry and Psychotherapy, Tübingen Center for Mental Health, University Hospital Tübingen, Tübingen, Germany.
Binder G; Pediatric Endocrinology, University Children`s Hospital Tübingen, Tübingen, Germany.

Front Endocrinol (Lausanne) ; 13: 897897, 2022.

Article in En | MEDLINE | ID: mdl-35769084

Subject(s)

DNA Methylation; Human Growth Hormone; Insulin-Like Growth Factor I; Turner Syndrome; Body Height/genetics; Child; Human Growth Hormone/deficiency; Human Growth Hormone/therapeutic use; Humans; Infant, Small for Gestational Age; Insulin-Like Growth Factor I/genetics; Insulin-Like Growth Factor I/metabolism; Promoter Regions, Genetic; Turner Syndrome/drug therapy; Turner Syndrome/genetics; Turner Syndrome/metabolism

Key words

GH response; GH treatment; IGF-1; prediction; promotor methylation; short stature

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Turner Syndrome / Insulin-Like Growth Factor I / Human Growth Hormone / DNA Methylation Type of study: Prognostic_studies Limits: Child / Humans Language: En Journal: Front Endocrinol (Lausanne) Year: 2022 Type: Article Affiliation country: Germany

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