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Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer's disease mouse model.
Freitag, Kiara; Sterczyk, Nele; Wendlinger, Sarah; Obermayer, Benedikt; Schulz, Julia; Farztdinov, Vadim; Mülleder, Michael; Ralser, Markus; Houtman, Judith; Fleck, Lara; Braeuning, Caroline; Sansevrino, Roberto; Hoffmann, Christian; Milovanovic, Dragomir; Sigrist, Stephan J; Conrad, Thomas; Beule, Dieter; Heppner, Frank L; Jendrach, Marina.
Affiliation
  • Freitag K; Department of Neuropathology, Charité, Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Berlin Institute of Health, Berlin, Germany.
  • Sterczyk N; German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association, Berlin, Germany.
  • Wendlinger S; Department of Neuropathology, Charité, Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Berlin Institute of Health, Berlin, Germany.
  • Obermayer B; Department of Neuropathology, Charité, Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Berlin Institute of Health, Berlin, Germany.
  • Schulz J; Department of Biosciences, University of Salzburg, Salzburg, Austria.
  • Farztdinov V; Core Unit Bioinformatics, Berlin Institute of Health at Charité, Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany.
  • Mülleder M; Department of Neuropathology, Charité, Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Berlin Institute of Health, Berlin, Germany.
  • Ralser M; Core Facility, High-Throughput Mass Spectrometry, Charité, Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.
  • Houtman J; Core Facility, High-Throughput Mass Spectrometry, Charité, Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.
  • Fleck L; Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, UK.
  • Braeuning C; Department of Biochemistry, Charité, Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.
  • Sansevrino R; Department of Neuropathology, Charité, Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Berlin Institute of Health, Berlin, Germany.
  • Hoffmann C; Department of Neuropathology, Charité, Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, Berlin Institute of Health, Berlin, Germany.
  • Milovanovic D; Genomics Technology Platform, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.
  • Sigrist SJ; Berlin Institute of Health (BIH), Berlin, Germany.
  • Conrad T; Laboratory of Molecular Neuroscience, German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association, Berlin, Germany.
  • Beule D; Laboratory of Molecular Neuroscience, German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association, Berlin, Germany.
  • Heppner FL; Laboratory of Molecular Neuroscience, German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association, Berlin, Germany.
  • Jendrach M; German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association, Berlin, Germany.
J Neuroinflammation ; 19(1): 172, 2022 Jul 02.
Article in En | MEDLINE | ID: mdl-35780157
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spermidine / Amyloid beta-Peptides / Alzheimer Disease Limits: Animals Language: En Journal: J Neuroinflammation Journal subject: NEUROLOGIA Year: 2022 Type: Article Affiliation country: Germany
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spermidine / Amyloid beta-Peptides / Alzheimer Disease Limits: Animals Language: En Journal: J Neuroinflammation Journal subject: NEUROLOGIA Year: 2022 Type: Article Affiliation country: Germany