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Resolving m6A epitranscriptome with stoichiometry.
Yoon, Ki-Jun; Kim, Yoon Ki.
Affiliation
  • Yoon KJ; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea; KAIST Stem Cell Center, KAIST, Daejeon 34141, Republic of Korea. Electronic address: kijunyoon@kaist.ac.kr.
  • Kim YK; Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea; Creative Research Initiatives Center for Molecular Biology of Translation, Korea University, Seoul, Republic of Korea; Division of Life Sciences, Korea University, Seoul 02841, Republic of Korea. Electronic address: yk-kim@korea.ac.kr.
Trends Genet ; 38(11): 1099-1100, 2022 11.
Article in En | MEDLINE | ID: mdl-35792016
A recent study by Hu et al. describes N6-methyladenosine (m6A)-selective allyl chemical labeling and sequencing (m6A-SAC-seq), which allows for quantitative, stoichiometric, and positional analyses of m6A at single-nucleotide resolution across the whole transcriptome level. Information on the m6A stoichiometry will provide additional layers of gene regulatory pathways mediated by m6A modification during diverse molecular, cellular, and physiological events.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenosine / Transcriptome Language: En Journal: Trends Genet Journal subject: GENETICA Year: 2022 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenosine / Transcriptome Language: En Journal: Trends Genet Journal subject: GENETICA Year: 2022 Type: Article