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Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities.
Mallard, Travis T; Linnér, Richard Karlsson; Grotzinger, Andrew D; Sanchez-Roige, Sandra; Seidlitz, Jakob; Okbay, Aysu; de Vlaming, Ronald; Meddens, S Fleur W; Palmer, Abraham A; Davis, Lea K; Tucker-Drob, Elliot M; Kendler, Kenneth S; Keller, Matthew C; Koellinger, Philipp D; Harden, K Paige.
Affiliation
  • Mallard TT; Department of Psychology, University of Texas at Austin, Austin, TX, USA.
  • Linnér RK; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Grotzinger AD; Lead contact.
  • Sanchez-Roige S; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Seidlitz J; Autism and Developmental Medicine Institute, Geisinger, Lewisburg, PA, USA.
  • Okbay A; Department of Psychology, University of Texas at Austin, Austin, TX, USA.
  • de Vlaming R; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.
  • Meddens SFW; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Palmer AA; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.
  • Davis LK; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Tucker-Drob EM; Department of Economics, School of Business and Economics, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Kendler KS; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, the Netherlands.
  • Koellinger PD; Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.
  • Harden KP; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA.
Cell Genom ; 2(6)2022 Jun 08.
Article in En | MEDLINE | ID: mdl-35812988
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Cell Genom Year: 2022 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Cell Genom Year: 2022 Type: Article Affiliation country: United States