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BRD4 inhibition by JQ1 protects against LPS-induced cardiac dysfunction by inhibiting activation of NLRP3 inflammasomes.
Li, Wenjun; Shen, XiuFeng; Feng, Shenglan; Liu, Yue; Zhao, Huiying; Zhou, Guohao; Sang, Ming; Sun, Xiaodong; Jiao, Rong; Liu, Fuyuan.
Affiliation
  • Li W; Department of Cardiology, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Hubei Province, Xiangyang, 441500, People's Republic of China.
  • Shen X; Department of Cardiology, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Hubei Province, Xiangyang, 441500, People's Republic of China.
  • Feng S; Department of Basic Medicine, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Hubei Province, Xiangyang, 441500, People's Republic of China.
  • Liu Y; Department of Pediatrics, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Hubei Province, Xiangyang, 441500, People's Republic of China.
  • Zhao H; Department of Cardiology, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Hubei Province, Xiangyang, 441500, People's Republic of China.
  • Zhou G; Department of Cardiology, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Hubei Province, Xiangyang, 441500, People's Republic of China.
  • Sang M; Department of Basic Medicine, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Hubei Province, Xiangyang, 441500, People's Republic of China.
  • Sun X; Department of Basic Medicine, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Hubei Province, Xiangyang, 441500, People's Republic of China.
  • Jiao R; Department of Pediatrics, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Hubei Province, Xiangyang, 441500, People's Republic of China. jiaorong1125@163.com.
  • Liu F; Department of Cardiology, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Hubei Province, Xiangyang, 441500, People's Republic of China. LFY0053@163.com.
Mol Biol Rep ; 49(9): 8197-8207, 2022 Sep.
Article in En | MEDLINE | ID: mdl-35854052
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein / Heart Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Biol Rep Year: 2022 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein / Heart Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Biol Rep Year: 2022 Type: Article