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Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection.
Cui, Zhifen; Zeng, Cong; Huang, Furong; Yuan, Fuwen; Yan, Jingyue; Zhao, Yue; Zhou, Yufan; Hankey, William; Jin, Victor X; Huang, Jiaoti; Staats, Herman F; Everitt, Jeffrey I; Sempowski, Gregory D; Wang, Hongyan; Dong, Yizhou; Liu, Shan-Lu; Wang, Qianben.
Affiliation
  • Cui Z; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
  • Zeng C; Viruses and Emerging Pathogens Program, Infectious Diseases Institute, Center for Retrovirus Research and Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA.
  • Huang F; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
  • Yuan F; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
  • Yan J; Division of Pharmaceutics and Pharmacology, College of Pharmacy and Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USA.
  • Zhao Y; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
  • Zhou Y; Department of Pathology, College of Basic Medical Sciences and First Affiliated Hospital, China Medical University, Shenyang, China.
  • Hankey W; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
  • Jin VX; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
  • Huang J; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
  • Staats HF; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
  • Everitt JI; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
  • Sempowski GD; Duke Human Vaccine Institute and Regional Biocontainment Laboratory, Duke University School of Medicine, Durham, NC, USA.
  • Wang H; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
  • Dong Y; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
  • Liu SL; Duke Human Vaccine Institute and Regional Biocontainment Laboratory, Duke University School of Medicine, Durham, NC, USA.
  • Wang Q; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
Nat Chem Biol ; 18(10): 1056-1064, 2022 10.
Article in En | MEDLINE | ID: mdl-35879545
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Drug Treatment Limits: Animals Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2022 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Drug Treatment Limits: Animals Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2022 Type: Article Affiliation country: United States