A Synergistic Effect of Phthalimide-Substituted Sulfanyl Porphyrazines and Carbon Nanotubes to Improve the Electrocatalytic Detection of Hydrogen Peroxide.
Molecules
; 27(14)2022 Jul 09.
Article
in En
| MEDLINE
| ID: mdl-35889282
ABSTRACT
A sulfanyl porphyrazine derivative with peripheral phthalimide moieties was metallated with cobalt(II) and iron(II) metal ions. The purity of the macrocycles was confirmed by HPLC, and subsequently, compounds were characterized using various analytical methods (ES-TOF, MALDI-TOF, UV-VIS, and NMR spectroscopy). To obtain hybrid electroactive electrode materials, novel porphyrazines were combined with multiwalled carbon nanotubes. The electrocatalytic effect derived from cobalt(II) and iron(II) cations was evaluated. As a result, a significant decrease in the overpotential was observed compared with that obtained with bare glassy carbon (GC) or glassy carbon electrode/carbon nanotubes (GC/MWCNTs), which allowed for sensitive determination of hydrogen peroxide in neutral conditions (pH 7.4). The prepared sensor enables a linear response to H2O2 concentrations of 1-90 µM. A low detection limit of 0.18 µM and a high sensitivity of 640 µA mM-1 cm-2 were obtained. These results indicate that the obtained sensors could potentially be applied in biomedical and environmental fields.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Nanotubes, Carbon
Type of study:
Diagnostic_studies
Language:
En
Journal:
Molecules
Journal subject:
BIOLOGIA
Year:
2022
Type:
Article
Affiliation country:
Poland