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A phase III, multicenter, double-blind, randomized clinical trial to evaluate the efficacy and safety of ceftolozane/tazobactam plus metronidazole versus meropenem in Chinese participants with complicated intra-abdominal infections.
Sun, Yihong; Fan, Jia; Chen, Gang; Chen, Xiaofei; Du, Xiaoling; Wang, Ye; Wang, Hui; Sun, Fang; Johnson, Matthew G; Bensaci, Mekki; Huntington, Jennifer A; Bruno, Christopher J.
Affiliation
  • Sun Y; Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
  • Fan J; Department of Liver Surgery and Transplantation, Zhongshan Hospital, Fudan University, Shanghai, China. Electronic address: fan.jia@zs-hospital.sh.cn.
  • Chen G; Department of Hepatobiliary Surgery, The First Hospital of Kunming, Kunming, China.
  • Chen X; MSD China, Building A, Headquarters Park Phase II, No. 1582 Gumei Rd, Xuhui District, Shanghai 200233 China.
  • Du X; MSD China, Building A, Headquarters Park Phase II, No. 1582 Gumei Rd, Xuhui District, Shanghai 200233 China.
  • Wang Y; MSD China, Building A, Headquarters Park Phase II, No. 1582 Gumei Rd, Xuhui District, Shanghai 200233 China.
  • Wang H; MSD China, Building A, Headquarters Park Phase II, No. 1582 Gumei Rd, Xuhui District, Shanghai 200233 China.
  • Sun F; MSD China, Building A, Headquarters Park Phase II, No. 1582 Gumei Rd, Xuhui District, Shanghai 200233 China.
  • Johnson MG; Merck & Co., Inc., Rahway, NJ, USA.
  • Bensaci M; Merck & Co., Inc., Rahway, NJ, USA.
  • Huntington JA; Merck & Co., Inc., Rahway, NJ, USA.
  • Bruno CJ; Merck & Co., Inc., Rahway, NJ, USA. Electronic address: christopher.bruno@merck.com.
Int J Infect Dis ; 123: 157-165, 2022 Oct.
Article in En | MEDLINE | ID: mdl-35987467
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Intraabdominal Infections / Metronidazole Type of study: Clinical_trials Limits: Adult / Humans Country/Region as subject: Asia Language: En Journal: Int J Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2022 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Intraabdominal Infections / Metronidazole Type of study: Clinical_trials Limits: Adult / Humans Country/Region as subject: Asia Language: En Journal: Int J Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2022 Type: Article Affiliation country: China