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Effector Th1 cells under PD-1 and CTLA-4 checkpoint blockade abrogate the upregulation of multiple inhibitory receptors and by-pass exhaustion.
Horzum, Utku; Yanik, Hamdullah; Taskiran, Ekim Z; Esendagli, Gunes.
Affiliation
  • Horzum U; Department of Basic Oncology, Hacettepe University Cancer Institute, Ankara, Turkey.
  • Yanik H; Division of Molecular Pathophysiology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
  • Taskiran EZ; Department of Basic Oncology, Hacettepe University Cancer Institute, Ankara, Turkey.
  • Esendagli G; Department of Medical Genetics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Immunology ; 167(4): 640-650, 2022 12.
Article in En | MEDLINE | ID: mdl-36053975
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Cytotoxic / Programmed Cell Death 1 Receptor Language: En Journal: Immunology Year: 2022 Type: Article Affiliation country: Turkey
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Cytotoxic / Programmed Cell Death 1 Receptor Language: En Journal: Immunology Year: 2022 Type: Article Affiliation country: Turkey