Leucine-rich repeat kinase 2 is protective during acute kidney injury through its activation of autophagy in podocytes.

Wang, Jin-Ping; Yan, Ji-Ping; Xiao, Rui-Ling; Li, Rong-Shan

Wang, Jin-Ping; Yan, Ji-Ping; Xiao, Rui-Ling; Li, Rong-Shan.

Affiliation

Wang JP; Department of Ultrasound, Shanxi Province People's Hospital, Taiyuan, China.
Yan JP; Department of Ultrasound, Shanxi Province People's Hospital, Taiyuan, China.
Xiao RL; College of Safety and Emergency Management Engineering, Taiyuan University of Technology, Taiyuan, China.
Li RS; Department of Nephrology, Shanxi Province People's Hospital, Taiyuan, China.

Environ Toxicol ; 37(12): 2947-2956, 2022 Dec.

Article in En | MEDLINE | ID: mdl-36063080

Subject(s)

Acute Kidney Injury; Podocytes; Male; Mice; Animals; Podocytes/metabolism; Podocytes/pathology; Leucine; Lipopolysaccharides/pharmacology; Apoptosis; Autophagy; Acute Kidney Injury/metabolism; Biomarkers/metabolism

Key words

acute kidney injury; autophagy; ischemia-reperfusion; leucine-rich repeat kinase 2; lipopolysaccharide; podocytes

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Podocytes / Acute Kidney Injury Limits: Animals Language: En Journal: Environ Toxicol Journal subject: SAUDE AMBIENTAL / TOXICOLOGIA Year: 2022 Type: Article Affiliation country: China

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