Sex- and gender-differences in chronic long-term complications of type 1 and type 2 diabetes mellitus in Italy.
Nutr Metab Cardiovasc Dis
; 32(10): 2297-2309, 2022 10.
Article
in En
| MEDLINE
| ID: mdl-36064685
ABSTRACT
AIMS:
This review summarizes the contribution of Italian diabetologists devoted to a better understanding of the complex relationship linking sex/gender and long-term complications of type 1 (T1DM) and type 2 diabetes (T2DM) over the last fifteen years. DATASYNTHESIS:
Microvascular and macrovascular complications of diabetes show sex- and gender-related differences, involving pathophysiological mechanisms, epidemiological features and clinical presentation, due to the interaction between biological and psychosocial factors. These differences greatly impact on the progression of diabetes and its long-term complications, especially in the cardiovascular, renal and liver districts.CONCLUSION:
A better knowledge of such sex- and gender-related characteristics is required for a more precise patient phenotypization, and for the choice of a personalized antihyperglycemic treatment. Despite such mounting evidence, current diabetes clinical guidelines do not as yet adequately consider sex/gender differences.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Diabetes Complications
/
Diabetes Mellitus, Type 2
Type of study:
Diagnostic_studies
/
Guideline
Limits:
Humans
Country/Region as subject:
Europa
Language:
En
Journal:
Nutr Metab Cardiovasc Dis
Journal subject:
ANGIOLOGIA
/
CARDIOLOGIA
/
CIENCIAS DA NUTRICAO
/
METABOLISMO
Year:
2022
Type:
Article