Mathematical modelling of activation-induced heterogeneity in TNF, IL6, NOS2, and IL1ß expression reveals cell state transitions underpinning macrophage responses to LPS.

Dey, Shoumit; Boucher, Dave; Pitchford, Jon; Lagos, Dimitris

Dey, Shoumit; Boucher, Dave; Pitchford, Jon; Lagos, Dimitris.

Affiliation

Dey S; Hull York Medical School, University of York, York, UK.
Boucher D; Department of Biology, University of York, York, UK.
Pitchford J; Department of Mathematics, University of York, York, UK.
Lagos D; York Biomedical Research Institute, University of York, York, UK.

Wellcome Open Res ; 7: 29, 2022.

Article in En | MEDLINE | ID: mdl-36072059

Key words

IL1ß; IL6; NOS2; TNF; activation induced heterogeneity; macrophage heterogeneity; mathematical modelling

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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Wellcome Open Res Year: 2022 Type: Article Affiliation country: United kingdom

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