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A Consideration of Fixed Dosing Versus Body Size-Based Dosing Strategies for Chimeric Antigen Receptor T-Cell Therapies.
He, Jimmy Zhijian; Wang, Hechuan; Lim, KyoungSoo; Ren, Song; Rollins, Fred; Vallaster, Markus; Wong, Ryan; Stebbings, Richard; Standifer, Nathan; Keefe, Robert; Phipps, Alex; Gibbs, Megan.
Affiliation
  • He JZ; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA.
  • Wang H; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA.
  • Lim K; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA.
  • Ren S; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA.
  • Rollins F; Competitive Intelligence and Analysis, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA.
  • Vallaster M; Clinical Development, Cell Therapies and Immuno-Oncology, AstraZeneca, Waltham, Massachusetts, USA.
  • Wong R; Clinical Pharmacology and Safety Sciences, Biopharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Stebbings R; Clinical Pharmacology and Safety Sciences, Biopharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Standifer N; Integrated Bioanalysis, Clinical Pharmacology and Safety Sciences, Biopharmaceuticals R&D, AstraZeneca, South San Francisco, California, USA.
  • Keefe R; CMC Development, Cell Therapy, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA.
  • Phipps A; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Gibbs M; Clinical Pharmacology and Quantitative Pharmacology, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, USA.
Clin Pharmacol Drug Dev ; 11(10): 1130-1135, 2022 10.
Article in En | MEDLINE | ID: mdl-36094760
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Chimeric Antigen Limits: Humans Language: En Journal: Clin Pharmacol Drug Dev Year: 2022 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Chimeric Antigen Limits: Humans Language: En Journal: Clin Pharmacol Drug Dev Year: 2022 Type: Article Affiliation country: United States