Molecular inhibition of RAS signalling to target ageing and age-related health.

Laskovs, Mihails; Partridge, Linda; Slack, Cathy

Laskovs, Mihails; Partridge, Linda; Slack, Cathy.

Affiliation

Laskovs M; School of Biosciences, College of Health and Life Sciences, Aston University, Birmingham B4 7ET, UK.
Partridge L; Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK.
Slack C; Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Strasse 9b, 50931 Cologne, Germany.

Dis Model Mech ; 15(10)2022 10 01.

Article in En | MEDLINE | ID: mdl-36111627

Subject(s)

Antineoplastic Agents; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Neoplasms; Acarbose/therapeutic use; Aged; Antineoplastic Agents/pharmacology; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use; Neoplasms/drug therapy; Neoplasms/metabolism; ras Proteins/genetics

Key words

Ageing; MEK inhibitor; RAS pathway

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hydroxymethylglutaryl-CoA Reductase Inhibitors / Metformin / Neoplasms / Antineoplastic Agents Type of study: Prognostic_studies Limits: Aged / Humans Language: En Journal: Dis Model Mech Journal subject: MEDICINA Year: 2022 Type: Article Affiliation country: United kingdom

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